Potential role of anti-3S antibodies in an HIV medical cure strategy ?

February 4, 2013

Crouzet J, Vieillard V, Debré P, Katlama  C, Launay O, Ho Tsong Fang R, Desfontaines-Batéjat D, Marcu M, Gharakhanian  S.

Potential role of anti-3S antibodies in an HIV medical cure strategy ?.

Oral/Poster Presentation. HIV Cure & Eradication Workshop, 24-25 January 2013; Milan, Italy .

[Poster: distinguished as best poster of the Workshop].

We anticipate that HIV cure strategy will need to focus on a combined approach associating antivirals and immunotherapy. We have identified and developed a vaccine which has distinct immune-protective properties. We hypothesize that vaccine-induced anti-3S antibodies can have a key role in a multi-therapeutic approach to cure HIV. 3S antibodies will allow to shield the immune system and reconstruct physiologic immune homeostasis.